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Cleaved-Caspase-2 p18 (G170) rabbit pAb

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ES1016

规格：	价钱：
50?L	￥1280.00
100?L	￥1980.00

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Overview

产品名称:	Cleaved-Caspase-2 p18 (G170) rabbit pAb
反应性:	Human;Mouse;Rat
又名:	CASP2; ICH1; NEDD2; Caspase-2; CASP-2; Neural precursor cell expressed developmentally down-regulated protein 2; NEDD-2; Protease ICH-1
宿主:	Rabbit
稀释比:	Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
免疫原:	The antiserum was produced against synthesized peptide derived from human Caspase 2 p18 N-ternal. AA range:151-200
贮存条件:	-20°C/1 year
克隆性:	Polyclonal
抗体亚型:	IgG
浓度:	1 mg/ml
实测条带:	18 or 35kD
基因ID:	835
卵白序列:	P42575
细胞定位:	nucleus,cytoplasm,mitochondrion,cytosol,membrane,
研究配景:	This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer's disease, Huntington's disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011],

Western Blot analysis of various cells using Cleaved-Caspase-2 p18 (G170) Polyclonal Antibody diluted at 1:2000
Western Blot analysis of Jurkat cells using Cleaved-Caspase-2 p18 (G170) Polyclonal Antibody diluted at 1:2000
Western blot analysis of lysates from Jurkat cells, treated with etoposide 25uM 24h, using Caspase 2 (p18,Cleaved-Gly170) Antibody. The lane on the right is blocked with the synthesized peptide.

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