| 产品名称: |
Recombinant Mouse Asprosin (N-8His) |
| 产品形貌: |
Recombinant Mouse Fibrillin-1 is produced by our Mammalian expression system and the target gene encoding Ser2734-His2873 is expressed with a 8His tag at the N-terminus. |
| 卵白编号: |
AAA56840.1 |
| 分子量: |
16.9 KDa |
| 表观分子量: |
30 KDa, reducing conditions |
| 产品纯度: |
Greater than 85% as determined by reducing SDS-PAGE. |
| 内毒素: |
Less than 0.1 ng/?g (1 EU/?g) as determined by LAL test. |
| 复溶: |
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100μg/ml.
Dissolve the lyophilized protein in distilled water.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.? |
| 贮存条件: |
Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
| 运输条件: |
The product is shipped at ambient temperature.
Upon receipt, store it immediately at the temperature listed below. |
| 研究配景: |
Asprosin is a protein hormone that is produced by white adipose tissue in mammals (and potentially by other tissues), which is then transported to the liver and stimulates it to release glucose into the blood stream. In the liver asprosin activates rapid glucose release by a cAMP-dependent pathway. The glucose release by the liver into the blood stream is vital for brain function and survival during fasting. People with neonatal progeroid syndrome lack asprosin, while people with insulin resistance have it in abundance. In animal tests asprosin showed potential for treating type 2 diabetes. When antibodies targeting asprosin were injected into diabetic mice, blood glucose and insulin levels improved. |
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