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TRIpure总RNA提取试剂（同Trizol）

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EP013

规格：	价钱：
100mL	￥500.00
250mL	￥1000.00

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Overview 文献(283)

产品名称:	TRIpure Total RNA Extraction Reagent（As Trizol）
产品先容:	TRIpure?Total RNA Extraction Reagent?是一种用于种种动植物、细菌组织/细胞总RNA抽提的试剂，，，，具有极强的裂解能力，，，，可在短时间内裂解细胞和组织样本，，，，坚持样品中RNA的完整性，，，，有用抑制RNA的降解。。。样品在该试剂中能够充分被裂解，，，，在加入氯仿离心后，，，，溶液会形成上清层、中心层和有机层?(鲜红色下层)，，，，RNA漫衍在上层水相中，，，，网络上清层后，，，，经异丙醇沉淀便可接纳获得Total RNA。。。提取的总RNA纯度高，，，，基本不含卵白质及基因组DNA，，，，?可直接用于Northern、点杂交、mRNA纯化、体外翻译、RT-PCR、poly(A)+选择、RNA酶；；；；；て饰鲆约肮菇╟DNA文库等多种分子生物学实验。。。
产品特点:	提取质量高：可在1 h 内提取得率高、纯度高、完整性好的总RNA 添加指示剂：添加了特殊指示剂，，，，离心分层后下层为粉红色，，，，便于吸收上清迅速度高：对病毒等微量样本的提取具有更高的提取效率样品处置惩罚量无邪：对少量的组织(50-100mg)和细胞(5×10^6)以及大宗的组织(≥1g)和细胞(>10^7)均有较好的裂解效果。。。

Small

Cell-Free Extracts from Human Fat Tissue with a Hyaluronan-Based Hydrogel Attenuate Inflammation in a Spinal Cord Injury Model through M2 Microglia/Microphage Polarization

日期：2022-03-25 IF：15.153
Genes & Diseases

Glis1 regulates metabolic programming by promoting H3K18 lactylation to alleviate neuronal senescence following spinal cord injury

日期：2026-07-23 IF：14.46
Chemical Engineering Journal

Targeted delivery of stattic to pulmonary vascular smooth muscle cells ameliorates pulmonary arterial hypertension

日期：2026-04-24 IF：13.2
Chemical Engineering Journal

Exosome-loaded methacrylated silk fibroin hydrogel delays intervertebral disc degeneration by DKK2-mediated mitochondrial unfolded protein response

日期：2025-05-01 IF：13.2
Cancer Research

β-catenin Activation Reprograms Ammonia Metabolism to Promote Senescence Resistance in Hepatocellular Carcinoma

日期：2024-05-13 IF：11.2
BMC Medicine

Prolonged anesthesia induces neuroinflammation and complement-mediated microglial synaptic elimination involved in neurocognitive dysfunction and anxiety-like behaviors

日期：2023-01-05 IF：11.15
JOURNAL OF NANOBIOTECHNOLOGY

Peripheral nerves modulate the peri-implant osteogenesis under type 2 diabetes through exosomes derived from schwann cells via miR-15b-5p/Txnip signaling axis

日期：2025-01-28 IF：10.6
Journal of Nanobiotechnology

Chondrocyte-targeted exosome-mediated delivery of Nrf2 alleviates cartilaginous endplate degeneration by modulating mitochondrial fission

日期：2024-05-24 IF：10.6
Journal of Nanobiotechnology

MiR-144-5p, an exosomal miRNA from bone marrow-derived macrophage in type 2 diabetes, impairs bone fracture healing via targeting Smad1

日期：2021-07-30 IF：10.435
Advanced Healthcare Materials

ROS-Responsive Injectable Hydrogel Loaded with SLC7A11-modRNA Inhibits Ferroptosis and Mitigates Intervertebral Disc Degeneration in Rats

日期：2024-05-01 IF：10
Cancer Letters

Preoperative neoadjuvant targeted therapy remodels intra-tumoral heterogeneity of clear-cell renal cell carcinoma and ferroptosis inhibition induces resistance progression

日期：2024-05-18 IF：9.6
JOURNAL OF NANOBIOTECHNOLOGY

MiR-21 regulating PVT1/PTEN/IL-17 axis towards the treatment of infectious diabetic wound healing by modified GO-derived biomaterial in mouse models

日期：2022-06-28 IF：9.429
Chemosphere

Maternal exposure to bisphenol A induces fetal growth restriction via upregulating the expression of estrogen receptors.

日期：2021-09-11 IF：8.943
Frontiers in Immunology

Characterization of Immune-Related Molecular Subtypes and a Prognostic Signature Correlating With the Response to Immunotherapy in Patients With Gastric Cancer

日期：2022-07-08 IF：8.786
International Journal of Biological Macromolecules

A novel role of E2F transcription factor 1 in pancreatic stellate cell activation through polyamine metabolism modulation

日期：2026-02-12 IF：8.5
Frontiers of Medicine

A distinct “repair” role of regulatory T cells in fracture healing

日期：2024-03-16 IF：8.1
Biomaterials Research

Engineered exosomes enriched in netrin-1 modRNA promote axonal growth in spinal cord injury by attenuating inflammation and pyroptosis

日期：2023-01-17 IF：8.1
International Journal of Biological Macromolecules

HIF1α lactylation enhances KIAA1199 transcription to promote angiogenesis and vasculogenic mimicry in prostate cancer

日期：2022-10-06 IF：8.025
AGING CELL

Piezo1 exacerbates inflammation-induced cartilaginous endplate degeneration by activating mitochondrial fission via the Ca2+/CaMKII/Drp1 axis

日期：2025-05-27 IF：8
Journal of Orthopaedic Translation

Decellularized extracellular matrix restores Fibronectin/Integrin β1 balance through extracellular vesicles to rejuvenate chondrocytes and alleviate osteoarthritis progression

日期：2025-12-20 IF：7.8
Aging Cell

HIF-1α-induced expression of the m6A reader YTHDF1 inhibits the ferroptosis of nucleus pulposus cells by promoting SLC7A11 translation

日期：2024-05-23 IF：7.8
Biomedicine & Pharmacotherapy

Mesenchymal stem cell-derived exosomal microRNA-367–3p alleviates experimental autoimmune encephalomyelitis via inhibition of microglial ferroptosis by targeting EZH2

日期：2023-06-01 IF：7.419
BIOMEDICINE & PHARMACOTHERAPY

Metformin ameliorates olanzapine-induced insulin resistance via suppressing macrophage infiltration and inflammatory responses in rats

日期：2020-11-17 IF：7.419
Oxidative Medicine and Cellular Longevity

Sulforaphane Delays Intervertebral Disc Degeneration by Alleviating Endoplasmic Reticulum Stress in Nucleus Pulposus Cells via Activating Nrf-2/HO-1

日期：2023-01-07 IF：7.31
Oxidative Medicine and Cellular Longevity

Exosomal miR-224-5p from Colorectal Cancer Cells Promotes Malignant Transformation of Human Normal Colon Epithelial Cells by Promoting Cell Proliferation through Downregulation of CMTM4

日期：2022-06-30 IF：7.31
Oxid Med Cell Longev

Vagus Nerve Stimulation Attenuates Hepatic Ischemia/Reperfusion Injury via the Nrf2/HO-1 Pathway

日期：2019-03-28 IF：7.31
Journal of Genetics and Genomics

ATP6V1C1 deficiency impairs auditory and vestibular hair cell function and leads to sensorineural hearing loss in humans and mice

日期：2026-01-13 IF：7.1
Stem Cell Research & Therapy

BMSC-Exo miR-122-5p facilitates osteogenic differentiation of MC3T3-E1 cells through specifically suppressing SPRY2

日期：2024-09-13 IF：7.1
CNS Neuroscience & Therapeutics

Dihydroorotate dehydrogenase regulates ferroptosis in neurons after spinal cord injury via the P53-ALOX15 signaling pathway

日期：2023-03-22 IF：7.035
International Journal of Nanomedicine

Exosomal miR-133a-3p Derived from BMSCs Alleviates Cerebral Ischemia-Reperfusion Injury via Targeting DAPK2

日期：2023-01-05 IF：7.033
International Journal of Nanomedicine

Exosomal miR-136-5p Derived From AnlotinibResistant NSCLC Cells Confers Anlotinib Resistance in Non-Small Cell Lung Cancer Through Targeting PPP2R2A

日期：2021-06-07 IF：7.033
COMPUTERS IN BIOLOGY AND MEDICINE

Integrative multi-omics analysis of Crohn's disease and metabolic syndrome: Unveiling the underlying molecular mechanisms of comorbidity

日期：2024-12-01 IF：7
Food Science and Human Wellness

Hypoglycemic effect and the mechanism of action of a polysaccharide from sweet corncob in a high-fat diet and streptozotocin-induced diabetic mice

日期：2022-12-11 IF：7
Cell Biology and Toxicology

The method of sinus node?like pacemaker cells from human induced pluripotent stem cells by BMP and Wnt signaling

日期：2023-02-15 IF：6.819
Phytomedicine

Yinaoxin granule alleviates cerebral ischemia-reperfusion injury by ferroptosis inhibition through Nrf2 pathway activation

日期：2025-02-26 IF：6.7
Biomedicine & Pharmacotherapy

JNK downregulation improves olanzapine-induced insulin resistance by suppressing IRS1Ser307 phosphorylation and reducing inflammation

日期：2021-08-17 IF：6.529
Biomedicine & Pharmacotherapy

Over-expression of Kv4.3 gene reverses cardiac remodeling and transient-outward K+ current (Ito) reduction via CaMKII inhibition in myocardial infarction

日期：2020-11-02 IF：6.529
BIOMEDICINE & PHARMACOTHERAPY

Over-expression of Kv4. 3 gene reverses cardiac remodeling and transient-outward K+ current (Ito) reduction via CaMKII inhibition in myocardial infarction

日期：2020-11-02 IF：6.529
Cellular and Molecular Life Sciences

Fusobacterium nucleatum regulates nicotinamide metabolism via the upregulation of NNMT to activate PARP1/MAPK signalling in colitis-associated cancer

日期：2026-05-30 IF：6.5
Cellular and Molecular Life Sciences

Fusobacterium nucleatum regulates nicotinamide metabolism via the upregulation of NNMT to activate PARP1/MAPK signalling in colitis-associated cancer

日期：2026-05-30 IF：6.5
International Journal of Nanomedicine

Mesenchymal Stem Cells Attenuate Renal Fibrosis via Exosomes-Mediated Delivery of microRNA Let-7i-5p Antagomir

日期：2021-05-25 IF：6.4
Frontiers in Oncology

Bioinformatics, Molecular Docking and Experiments In Vitro Analyze the Prognostic Value of CXC Chemokines in Breast Cancer

日期：2021-05-26 IF：6.244
frontiers in oncology

Downregulation of miR-181b-5p Inhibits the Viability, Migration, and Glycolysis of Gallbladder Cancer by Upregulating PDHX Under Hypoxia

日期：2021-08-16 IF：6.244
Frontiers in Oncology

The Optimal Outcome of Suppressing Ewing Sarcoma Growth in vivo With Biocompatible Bioengineered miR-34a-5p Prodrug

日期：2020-02-25 IF：6.244
Translational Psychiatry

proBDNF expression induces apoptosis and inhibits synaptic regeneration by regulating the RhoA-JNK pathway in an in vitro post-stroke depression model

日期：2021-09-24 IF：6.222
EUROPACE

Ubiquitin-specific protease 38 promotes inflammatory atrial fibrillation induced by pressure overload

日期：2024-01-29 IF：6.1
Cell Biology and Toxicology

The method of sinus node-like pacemaker cells from human induced pluripotent stem cells by BMP and Wnt signaling

日期：2023-02-15 IF：6.1
Marine Drugs

Novel Prenylated Indole Alkaloids with Neuroprotection on SH-SY5Y Cells against Oxidative Stress Targeting Keap1–Nrf2

日期：2022-03-04 IF：6.085
Frontiers in Cell and Developmental Biology

Comprehensive Analysis of the Prognostic Significance of Hsa-miR-100-5p and Its Related Gene Signature in Stomach Adenocarcinoma

日期：2021-09-17 IF：6.081
Frontiers in Cellular and Infection Microbiology

New insights of necroptosis and immune infiltration in sepsis-induced myocardial dysfunction from bioinformatics analysis through RNA-seq in mice

日期：2022-12-21 IF：6.073
Frontiers in Cardiovascular Medicine

Blockade of Exosome Release Suppresses Atrial Fibrillation by Alleviating Atrial Fibrosis in Canines With Prolonged Atrial Pacing

日期：2021-10-15 IF：6.05
Frontiers in Cardiovascular Medicine

Knockdown of lnc-KCNC3-3:1 Alleviates the Development of Atherosclerosis via Downregulation of JAK1/STAT3 Signaling Pathway

日期：2021-11-03 IF：6.05
frontiers

Inhibition of KCa3.1 Channels Suppresses Atrial Fibrillation via the Attenuation of Macrophage Pro-inflammatory Polarization in a Canine Model With Prolonged Rapid Atrial Pacing

日期：2021-05-31 IF：6.05
Food and Chemical Toxicology

Inhibition of advanced glycation endproducts formation by lotus seedpod oligomeric procyanidins through RAGE-MAPK signaling and NF-κB activation in high-AGEs-diet mice

日期：2021-08-05 IF：6.023
CHINESE JOURNAL OF CHEMISTRY

Undescribed Meroterpenoids from Hypericum japonicum with Neuroprotective Effects on H2O2 Insult SH‐SY5Y Cells Targeting Keap1‐Nrf2

日期：2022-02-24 IF：6
CHINESE JOURNAL OF CHEMISTRY

Undescribed Meroterpenoids from Hypericum japonicum with Neuroprotective Effects on H2O2 Insult SH-SY5Y Cells Targeting Keap1-Nrf2

日期：2022-02-24 IF：6
Frontiers in Pharmacology

Fusobacterium nucleatum Activates Endoplasmic Reticulum Stress to Promote Crohn’s Disease Development via the Upregulation of CARD3 Expression

日期：2020-02-01 IF：5.988
Frontiers in Immunology

Proteomic and experimental analyses reveal molecular signatures of flexural atopic dermatitis in antecubital and popliteal fossae and the therapeutic effect of Aida lotion

日期：2026-03-31 IF：5.9
CELL BIOLOGY AND TOXICOLOGY

UBC9 mediates mitophagy to attenuate oxidative stress by regulating SUMOylation of PINK1 in the Parkinson’s disease progression

日期：2025-12-06 IF：5.9
Non-coding RNA Research

MicroRNA-541-3p/Rac2 signaling bridges radiation-induced lung injury and repair

日期：2025-01-27 IF：5.9
Cancer Gene Therapy

Loss of exosomal miR-200b-3p from hypoxia cancer-associated fibroblasts promotes tumorigenesis and reduces sensitivity to 5-Flourouracil in colorectal cancer via upregulation of ZEB1 and E2F3

日期：2023-03-08 IF：5.85
Frontiers in Cardiovascular Medicine

LINC00452 overexpression reverses oxLDL-induced injury of human umbilical vein endothelial cells (HUVECs) via regulating miR-194-5p/IGF1R axis

日期：2022-09-09 IF：5.846
Biochemical Pharmacology

miR-486-5p-rich extracellular vesicles derived from patients with olanzapine-induced insulin resistance negatively affect glucose-regulating function

日期：2024-05-22 IF：5.8
ACS Chemical Neuroscience

Inhibition of PINK1-Mediated Mitophagy Contributes to Postoperative Cognitive Dysfunction through Activation of Caspase-3/GSDME-Dependent Pyroptosis

日期：2023-03-22 IF：5.78
Helicobacter

Effects of sodium butyrate supplementation on inflammation, gut microbiota, and short-chain fatty acids in Helicobacter pylori-infected mice

日期：2021-02-20 IF：5.753
Frontiers in Aging Neuroscience

High-Fat Diet Alleviates Neuroinflammation and Metabolic Disorders of APP/PS1 Mice and the Intervention With Chinese Medicine

日期：2021-06-08 IF：5.75
Frontiers in Oncology

iRGD-modified exosomes-delivered BCL6 siRNA inhibit the progression of diffuse large B-cell lymphoma

日期：2022-08-02 IF：5.738
Frontiers in Oncology

microRNA-145-5p inhibits prostate cancer bone metastatic by modulating the epithelial-mesenchymal transition

日期：2022-09-06 IF：5.738
Genomics

Comparative profile of exosomal microRNAs in postmenopausal women with various bone mineral densities by small RNA sequencing

日期：2021-03-27 IF：5.736
International Immunopharmacology

Nesfatin-1, a novel energy-regulating peptide, alleviates pulmonary fibrosis by blocking TGF-β1/Smad pathway in an AMPKα-dependent manner

日期：2023-05-18 IF：5.714
International Immunopharmacology

Maresin1 ameliorates ventricular remodelling and arrhythmia in mice models of myocardial infarction via NRF2/HO-1 and TLR4/NF-kB signalling

日期：2022-10-21 IF：5.714
Frontiers in Immunology

Prognostic and immunotherapeutic potential of disulfidptosis-associated signature in pancreatic cancer

日期：2025-03-26 IF：5.7
Frontiers in Immunology

Unveiling the bioinformatic genes and their involved regulatory mechanisms in type 2 diabetes combined with osteoarthritis

日期：2024-08-08 IF：5.7
Aging-US

Ischemic postconditioning protects nonculprit coronary arteries against ischemia-reperfusion injury via downregulating miR-92a, miR-328 and miR-494

日期：2022-03-23 IF：5.682
Aging

Hsa_circ_0044226 knockdown attenuates progression of pulmonary fibrosis by inhibiting CDC27

日期：2021-07-24 IF：5.682
Aging

Curcumol may alleviate psoriasis-like inflammation by inhibiting keratinocyte proliferation and inflammatory gene expression via JAK1/STAT3 signaling

日期：2021-07-27 IF：5.682
Aging

LncRNA AC136007.2 alleviates cerebral ischemic-reperfusion injury by suppressing autophagy

日期：2021-08-13 IF：5.682
Aging

Knockdown of hsa_circ_0091994 constrains gastric cancer progression by suppressing the miR-324-5p/HMGA1 axis

日期：2021-08-24 IF：5.682
Aging

CXCL10 and its related key genes as potential biomarkers for psoriasis

日期：2021-09-24 IF：5.682
Experimental Neurology

Exosomal miR-23b-3p from bone mesenchymal stem cells alleviates experimental autoimmune encephalomyelitis by inhibiting microglial pyroptosis

日期：2023-05-01 IF：5.62
Food and Chemical Toxicology

Soluble thrombomodulin alleviates Diquat-induced acute kidney injury by inhibiting the HMGB1/IκBα/NF-κB signalling pathway

日期：2023-06-03 IF：5.572
Apoptosis

IRF-1-inhibited lncRNA XIST regulated the osteogenic differentiation via miR-450b/FBXW7 axis

日期：2023-01-17 IF：5.561
CNS Neuroscience & Therapeutics

Exosomal miR-128-3p reversed fibrinogen-mediated inhibition of oligodendrocyte progenitor cell differentiation and remyelination after cerebral ischemia

日期：2023-02-08 IF：5.5
Journal of Ethnopharmacology

Jiawei Qingxin Zishen Decoction mitigates granulosa cell apoptosis and enhances ovarian reserve through Netrin/UNC5B signaling pathway

日期：2025-10-02 IF：5.4
Diabetology &Metabolic Syndrome

Maternal hyperglycemia inhibits pulmonary vasculogenesis during mouse fetal lung development by promoting GβL Ubiquitination-dependent mammalian target of Rapamycin assembly

日期：2023-02-08 IF：5.4
Food & Function

Effect of punicalagin on multiple targets in streptozotocin/high-fat diet-induced diabetic mice

日期：2020-10-21 IF：5.396
Food & Function

Effect of punicalagin on multiple targets in streptozotocin/high-fat diet-induced diabetic mice

日期：2020-10-20 IF：5.396
Cell Death Discovery

Histone demethylase KDM4D inhibition suppresses renal cancer progression and angiogenesis through JAG1 signaling

日期：2021-10-11 IF：5.241
Cell Death Discovery

Itaconate inhibits ferroptosis of macrophage via Nrf2 pathways against sepsis-induced acute lung injury

日期：2022-02-02 IF：5.241
Microbial Biotechnology

Akkermansia muciniphila Alleviates Olanzapine-Induced Hepatic Steatosis via the Gut Microbiota-IGFBP2/APOA1-Liver Axis

日期：2025-12-10 IF：5.2
European Journal of Pharmacology

Pinocembrin ameliorates acute liver failure via activating the Sirt1/PPARα pathway in vitro and in vivo

日期：2022-01-15 IF：5.195
CHEMICO-BIOLOGICAL INTERACTIONS

HDAC6 inhibitor ACY-1215 improves neuropathic pain and its comorbidities in rats of peripheral nerve injury by regulating neuroinflammation

日期：2022-01-10 IF：5.194
Bioorganic Chemistry

Brassisterol A, a new ergosterol from co-cultivation of fungi attenuates neuroinflammation via targeting NLRP3/caspase-1/GSDMD pathway

日期：2023-10-29 IF：5.1
LIFE SCIENCES

CircClint1/miR-378b/NPDC1 axis: A novel therapeutic target and biomarker for myocardial infarction

日期：2026-05-08 IF：5.1
Cellular and Molecular Neurobiology

Sevoflurane Induces Learning and Memory Impairment in Young Mice Through a Reduction in Neuronal Glucose Transporter 3

日期：2019-12-28 IF：5.046
Life Sciences

Overexpression of microRNA-21-5p prevents the oxidative stress-induced apoptosis of RSC96 cells by suppressing autophagy

日期：2020-06-28 IF：5.037
Life Sciences

Icariin protects neurons from endoplasmic reticulum stress-induced apoptosis after OGD/R injury via suppressing IRE1α-XBP1 signaling pathway

日期：2020-05-25 IF：5.037
DRUG DEVELOPMENT RESEARCH

Tetrahydropalmatine induces the polarization of M1 macrophages to M2 to relieve limb ischemia-reperfusion-induced lung injury via inhibiting the TLR4/NF-κB/NLRP3 signaling pathway

日期：2022-08-17 IF：5.004
Drug Development Research

Knockdown of IGF2BP3 inhibits the tumorigenesis of gallbladder cancer and modifies tumor microenvironment

日期：2022-10-02 IF：5.004
Scientific Reports

Vagus nerve stimulation attenuates acute kidney injury induced by hepatic ischemia/reperfusion injury in rats

日期：2022-12-15 IF：4.996
Scientific Reports

Vagus Nerve Stimulation Attenuates Acute Kidney Injury Induced by Hepatic Ischemia/Reperfusion Injury by Suppressing Inflammation, Oxidative Stress, and Apoptosis in Rats

日期：2022-08-17 IF：4.996
Molecules

Effect of Nanoparticles of DOX and miR-125b on DNA Damage Repair in Glioma U251 Cells and Underlying Mechanisms

日期：2022-09-07 IF：4.927
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Matrix Metalloproteinase 7 Mediates Epithelial–Mesenchymal Transition to Promote Liver Fibrosis Through E-cadherin/β-catenin Pathway in Biliary Atresia

日期：2026-02-26 IF：4.9
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Cellular Senescence in Hepatocellular Carcinoma: Immune Microenvironment Insights via Machine Learning and In Vitro Experiments

日期：2025-01-17 IF：4.9
CNS Neuroscience & Therapeutics

The Circadian Clock Gene Bmal1 Regulates Microglial Pyroptosis After Spinal Cord Injury via NF-κB/MMP9

日期：2024-12-08 IF：4.8
International Immunopharmacology

METTL3-mediated m6A modification of CD36: Implications for glucose metabolism and inflammatory dysregulation in follicles of polycystic ovary syndrome

日期：2024-12-25 IF：4.8
International Immunopharmacology

Epimedii Folium decoction ameliorates osteoporosis in mice through NLRP3/caspase-1/IL-1β signalling pathway and gut-bone axis

日期：2024-08-20 IF：4.8
Stem Cell Reviews and Reports

MSC-Derived Exosomes Ameliorate Intervertebral Disc Degeneration By Regulating the Keap1/Nrf2 Axis

日期：2023-08-01 IF：4.8
Pharmaceuticals

Loureirin B Attenuates Methotrexate-Induced Liver Injury Associated with Oxidative Stress, SIRT1 Alterations, and TGF-β/SMAD3-Related Profibrotic Responses

日期：2026-06-02 IF：4.8
Frontiers in Pharmacology

Seawater pearl hydrolysate alleviates perimenopausal syndrome by modulating hypothalamic and uterine ERα/MAPK/CREB signaling in ovariectomized rats

日期：2026-03-06 IF：4.8
CANCER BIOLOGY & THERAPY

MiR-376a-3p increases cell apoptosis in acute myeloid leukemia by targeting MT1X

日期：2022-03-22 IF：4.742
International Immunopharmacology

Cepharanthine protects against lipopolysaccharide-induced acute lung injury in mice by blocking NLRP3 inflammasome activation

日期：2026-03-11 IF：4.7
International Immunopharmacology

Circular RNA PVT1 promotes osteoarthritis progression through the miR-550a-3p/CX3CR1 pathway: A mechanistic study

日期：2025-07-18 IF：4.7
iScience

Behenic acid alleviates inflammation and insulin resistance in gestational diabetes mellitus by regulating TLR4/NF-κB signaling pathway

日期：2024-10-18 IF：4.6
Scientific Reports

Comprehensive analyses of solute carrier family members identify SLC12A2 as a novel therapy target for colorectal cancer

日期：2024-02-23 IF：4.6
Frontiers in Physiology

Blocking Intermediate-Conductance Calcium-Activated Potassium Channels in the Macrophages Around Ganglionated Plexi Suppresses Atrial Fibrillation Vulnerability in Canines With Rapid Atrial Pacing

日期：2022-04-01 IF：4.566
Adipocyte

The mechanisms underlying olanzapine-induced insulin resistance via the brown adipose tissue and the therapy in rats

日期：2022-01-22 IF：4.534
Mediators of Inflammation

Tumor Necrosis Factor-α Promotes the Tumorigenesis, Lymphangiogenesis, and Lymphatic Metastasis in Cervical Cancer via Activating VEGFC-Mediated AKT and ERK Pathways

日期：2023-04-21 IF：4.529
Molecular Pharmaceutics

Insulin-Induced Gene 1-Enhance Secretion of BMSC Exosome Enriched in miR-132–3p Promoting Wound Healing in Diabetic Mice

日期：2024-08-13 IF：4.5
Environmental Toxicology

Cuproptosis-related lncRNAs ovarian cancer: Multi-omics analysis of molecular mechanisms and potential therapeutic targets

日期：2023-11-29 IF：4.5
Journal of Functional Foods

Anti-renal fibrosis and anti-inflammation effect of urolithin B, ellagitannin-gut microbial-derived metabolites in unilateral ureteral obstruction rats

日期：2021-11-19 IF：4.451
Journal of Functional Foods

Urolithin A attenuates renal fibrosis by inhibiting TGF-β1/Smad and MAPK signaling pathways

日期：2021-05-18 IF：4.451
frontiers in oncology

Curcumin in Combination With Omacetaxine Suppress Lymphoma Cell Growth, Migration, Invasion, and Angiogenesis via Inhibition of VEGF/Akt Signaling Pathway

日期：2021-08-11 IF：4.451
JOURNAL OF CELLULAR BIOCHEMISTRY

miR-145 attenuates cardiac fibrosis through the AKT/GSK-3β/β-catenin signaling pathway by directly targeting SOX9 in fibroblasts

日期：2020-09-05 IF：4.429
Probiotics and Antimicrobial Proteins

The Anti-inflammatory, Antioxidant Effects and Protective Barrier Function of Cell-Free Supernatant of Potential Probiotic Staphylococcus epidermidis CCSM0322 in HaCaT Cell Induced by UVB

日期：2025-12-15 IF：4.4
Cellular Signalling

SIRT6 mitigates acute kidney injury by enhancing lipid metabolism and reducing tubular epithelial cell apoptosis via suppression of the ACMSD signaling pathway

日期：2025-03-31 IF：4.4
Frontiers in Pharmacology

Tomatidine relieves neuronal damage in spinal cord injury by inhibiting the inflammatory responses and apoptosis through blocking the NF-κB/CXCL10 pathway activation

日期：2024-12-12 IF：4.4
Poultry Science

Melatonin alleviates endoplasmic reticulum stress to improve ovarian function by regulating the mTOR pathway in aged laying hens

日期：2024-06-26 IF：4.4
Poultry Science

Melatonin alleviates endoplasmic reticulum stress and follicular granulosa cell apoptosis by regulating ATF4 to activate mTOR signaling pathway in chickens

日期：2024-03-15 IF：4.4
Life Science Alliance

tRF-1:30-Gly-CCC-3 inhibits thyroid cancer via binding to PC and modulating metabolic reprogramming

日期：2023-12-11 IF：4.4
Journal of Oncology

Overexpressed lncRNA LINC00893 Suppresses Progression of Colon Cancer by Binding with miR-146b-3p to Upregulate PRSS8

日期：2022-05-05 IF：4.375
Drug Design Development and Therapy

Exosomes Derived from Hypoxic Glioma Cells Reduce the Sensitivity of Glioma Cells to Temozolomide Through Carrying miR-106a-5p

日期：2022-12-14 IF：4.319
Drug Design Development and Therapy

Exosomes Derived from Hypoxic Glioma Cells Reduce the Sensitivity of Glioma Cells to Temozolomide Through Carrying miR-106a-5p

日期：2022-10-13 IF：4.319
Frontiers in Physiology

Reduced activity of two LPL C-terminal variants, p.Glu396Val and novel p.Trp417Cys: a clinical, biochemical and structural study

日期：2026-06-10 IF：4.3
Biology of Reproduction

Par3/integrin β1 regulates embryo adhesion via changing endometrial luminal epithelium polarity

日期：2021-03-02 IF：4.285
Frontiers in Pharmacology

Fusobacterium nucleatum activates endoplasmic reticulum stress to promote crohn's disease development via the upregulation of CARD3 expression

日期：2020-02-21 IF：4.225
Journal of Ovarian Research

insenoside Rb2 improves diminished ovarian reserve through regulation of gonadal hormones and apoptosis via SIRT1

日期：2026-03-31 IF：4.2
FASEB JOURNAL

TFAM-Associated Mitochondrial Dynamics and Metabolic Reprogramming Regulate Microglial Polarization: Temporal and Causal Perspectives

日期：2026-01-22 IF：4.2
Experimental Neurology

KIF23 inhibition protects against perioperative neurocognitive disorders by hindering ROS/caspase-3/GSDME-mediated pyroptosis

日期：2025-07-06 IF：4.2
Human Cell

Exosomal microRNA-551b-3p from bone marrow-derived mesenchymal stromal cells inhibits breast cancer progression via regulating TRIM31/Akt signaling

日期：2022-08-09 IF：4.174
Human Cell

Exosomes derived from mesenchymal stem cells ameliorate renal fibrosis via delivery of miR-186-5p

日期：2021-09-16 IF：4.174
Human Cell

MiR-27b-3p inhibits the progression of renal fibrosis via suppressing STAT1

日期：2020-12-14 IF：4.174
International Journal of Molecular Medicine

Knockdown of mesenchymal stem cell?derived exosomal LOC100129516 suppresses the symptoms of atherosclerosis via upregulation of the PPARγ/LXRα/ABCA1 signaling pathway

日期：2021-10-04 IF：4.101
Frontiers in Molecular Biosciences

Screening of potential oxidative stress-related biomarkers and therapeutic drugs in rheumatoid arthritis based on integrative bioinformatics, machine learning, and molecular dynamics simulations

日期：2026-03-30 IF：4
FASEB JOURNAL

Enhancing high-quality fat survival: A novel strategy using cell-free fat extract

日期：2024-07-12 IF：4
Heliyon

Nicotine plays a protective role in rats with induced viral pneumonia with polyinosinic-polycytidylic acid through α7nAChR

日期：2023-10-26 IF：4
Journal of Reproductive Immunology

YY1/ITGA3 pathway may affect trophoblastic cells migration and invasion ability

日期：2022-07-26 IF：3.993
Cancer Management and Research

Hypoxic Breast Cancer Cell-Derived Exosomal SNHG1 Promotes Breast Cancer Growth and Angiogenesis via Regulating miR-216b-5p/JAK2 Axis

日期：2022-01-07 IF：3.989
Gene

Identification of immunity- and ferroptosis-related genes for predicting the prognosis of serous ovarian cancer

日期：2022-07-02 IF：3.913
Biomedicines

Comprehensive Analysis of N6-Methyladenosine Methylation in Transverse Aortic Constriction-Induced Cardiac Fibrosis Based on MeRIP-Seq Analysis

日期：2025-08-20 IF：3.9
Frontiers in Endocrinology

Identification of mitochondria-related feature genes for predicting type 2 diabetes mellitus using machine learning methods

日期：2025-03-27 IF：3.9
Food Science & Nutrition

Vitamin D Attenuates Inflammation and Mitochondrial Dysfunction in Experimental Models Relevant to Connective Tissue Disease–Associated Pulmonary Arterial Hypertension

日期：2026-03-12 IF：3.8
Journal of Ovarian Research

Icariside II induces ferroptosis through the down-regulation of SLC7A11 in ovarian cancer

日期：2025-04-05 IF：3.8
Scientific Reports

Seminal plasma exosome derived miR-26-5p can regulate decidual macrophage polarization via PTEN / PI3K / AKT signaling pathway

日期：2025-03-17 IF：3.8
Scientific Reports

Interpretable machine learning-driven biomarker identification and validation for Alzheimer’s disease

日期：2024-12-28 IF：3.8
Scientific Reports

Unlocking the Therapeutic Potential of 1,25(OH)?D?: Targeting Ferroptosis to Alleviate Lumbar Intervertebral Disc Degeneration

日期：2024-12-22 IF：3.8
Scientific Reports

Seminal plasma exosome-derived miR-26-5p promotes embryo implantation and development by regulating decidual macrophage polarization via PTEN / PI3K / AKT signaling pathway

日期：2024-10-03 IF：3.8
scientific reports

Discussion of spinal cord neurons apoptosis and neuroprotection mechanism of NGF gene transfection mediated by recombinant adenovirus in EAE mice

日期：2024-09-12 IF：3.8
Functional & Integrative Genomics

Reversal of H2O2-induced cell death by knockdown of HOTAIR in HTR-8/SVneo cells by mediation of miR-106b-5p/ACSL4 axis

日期：2023-05-15 IF：3.674
Functional & Integrative Genomics

Astragaloside IV suppresses the migration and EMT progression of cervical cancer cells by inhibiting macrophage M2 polarization through TGFβ/Smad2/3 signaling

日期：2023-04-21 IF：3.67
CELL BIOLOGY INTERNATIONAL

Methylation of miR‐19b‐3p promoter exacerbates inflammatory responses in sepsis‐induced ALI via targeting KLF7

日期：2021-03-24 IF：3.612
Cell and Tissue Research

Long noncoding RNA XIST inhibition promotes Leydig cell apoptosis by acting as a competing endogenous RNA for microRNA-145a-5p that targets SIRT1 in late-onset hypogonadism

日期：2024-02-14 IF：3.6
Biochemical and Biophysical Research Communications

Colchicine prevents ventricular arrhythmias vulnerability in diet-induced obesity rats

日期：2022-04-16 IF：3.575
Biochemical and Biophysical Research Communications

Exosomal long non-coding RNA LIPCAR derived from oxLDL-treated THP-1 cells regulates the proliferation of human umbilical vein endothelial cells and human vascular smooth muscle cells

日期：2021-08-26 IF：3.575
Pharmaceutical Biology

Icariin inhibits the expression of IL-1β, IL-6 and TNF-α induced by OGD/R through the IRE1/XBP1s pathway in microglia

日期：2021-10-06 IF：3.503
Frontiers in Molecular Neuroscience

Exploring hypoxia-related genes in spinal cord injury: a pathway to new therapeutic targets

日期：2025-05-20 IF：3.5
Immunity Inflammation and Disease

Thrombospondin-4 Regulates Lipopolysaccharide-Induced Apoptosis and Inflammation in Nucleus Pulposus Cells via the Phosphatidylinositol 3-Kinase/Protein Kinase B Pathway

日期：2026-07-06 IF：3.5
DISEASE MARKERS

Role of Cardiomyocyte-Derived Exosomal MicroRNA-146a-5p in Macrophage Polarization and Activation

日期：2022-05-02 IF：3.434
Disease Markers

Combined Transcriptomic and Metabolomic Analysis of Women with Polycystic Ovary Syndrome

日期：2022-08-28 IF：3.434
Molecular Medicine Reports

LncRNA LINC00961 regulates endothelial?mesenchymal transition via the PTEN?PI3K?AKT pathway

日期：2022-06-02 IF：3.423
EUROPEAN JOURNAL OF MEDICAL RESEARCH

Tanshinone IIA induces ferroptosis in colorectal cancer cells through the suppression of SLC7A11 expression via the PI3K/AKT/mTOR pathway

日期：2025-07-05 IF：3.4
Heliyon

Atrial fibroblast-derived exosomal miR-21 upregulate myocardial KCa3.1 via the PI3K-Akt pathway during rapid pacing

日期：2024-06-14 IF：3.4
JOURNAL OF PERIODONTAL RESEARCH

Low-energy red light-emitting diode irradiation enhances osteogenic differentiation of periodontal ligament stem cells by regulating miR-146a-5p

日期：2024-06-06 IF：3.4
European Review for Medical and Pharmacological Sciences

Roxadustat protects rat renal tubular epithelial cells from hypoxia-induced injury through the TGF-β1/Smad3 signaling pathway

日期：2023-12-01 IF：3.3
HEREDITAS

Identification of key apoptosis-related genes and immune infiltration in the pathogenesis of psoriasis

日期：2022-06-22 IF：3.271
JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Metformin Attenuates Hypoxia-induced Endothelial Cell Injury by Activating the AMP-Activated Protein Kinase Pathway

日期：2021-06-01 IF：3.271
Bioengineered

Chronic Sigma 1 receptor activation alleviates right ventricular dysfunction secondary to pulmonary arterial hypertension

日期：2022-04-27 IF：3.269
Bioengineered

Knockdown of lncRNA PCAT6 suppresses the growth of non-small cell lung cancer cells by inhibiting macrophages M2 polarization via miR-326/KLF1 axis

日期：2022-05-24 IF：3.269
Bioengineered

Exosomes from miR-374a-5p-modified mesenchymal stem cells inhibit the progression of renal fibrosis by regulating MAPK6/MK5/YAP axis

日期：2022-02-09 IF：3.269
Bioengineered

Exosomal microRNA-618 derived from mesenchymal stem cells attenuate the progression of hepatic fibrosis by targeting Smad4

日期：2022-02-24 IF：3.269
Biomed Research International

Propranolol Suppresses Proliferation and Migration of HUVECs through Regulation of the miR-206/VEGFA Axis

日期：2021-10-16 IF：3.246
IUBMB LIFE

Unveiling Gamma-Interferon-Inducible Lysosomal Thiol Reductase (IFI30) as a Regulator of Macrophage Polarization and Prognostic Biomarker by Multi-Transcriptome Analysis in Cervical Cancer

日期：2025-08-28 IF：3.2
MOLECULAR IMMUNOLOGY

UBE2I depletion regulated tumor-associated macrophage polarization into M1 type through reprogramming glycolysis and increases immunotherapy efficacy of anti-PD-L1 in ovarian cancer

日期：2025-01-31 IF：3.2
Immunity, Inflammation and Disease

Death receptor 3 is involved in preeclampsia through regulating placental trophoblast cell physiology by inactivating the PI3K/AKT pathway

日期：2023-09-27 IF：3.2
Iranian Journal of Basic Medical Sciences

Repurposing an antimicrobial arginine-rich decapeptide as a novel anticancer agent: Evidence from in vitro and in vivo breast cancer models

日期：2026-06-22 IF：3.2
Diabetes Metabolic Syndrome and Obesity-Targets and Therapy

Empagliflozin Regulates the AdipoR1/p-AMPK/p-ACC Pathway to Alleviate Lipid Deposition in Diabetic Nephropathy

日期：2021-01-18 IF：3.168
Oncology Letters

Connexin 43 overexpression induces lung cancer angiogenesis in vitro following phosphorylation at Ser279 in its C?terminus

日期：2022-07-05 IF：3.111
Cell Biology International

RFC4 Promotes the Metastasis of Colorectal Cancer by Regulating the Wnt/β-Catenin Pathway

日期：2026-01-23 IF：3.1
Cell Biology International

Sodium Tanshinone IIA Sulfonate Ameliorates Fibrosis of Skeletal Muscle Injury by Regulating Transforming Growth Factor-β1/Smad3 and Phosphoinositide 3-Kinase/protein Kinase B/Cyclooxygenase-2 Signaling Pathways

日期：2025-10-19 IF：3.1
Biochemical and Biophysical Research Communications

SIRT1 overexpression by melatonin and resveratrol combined treatment attenuates premature ovarian failure through activation of SIRT1/FOXO3a/BCL2 pathway

日期：2024-01-08 IF：3.1
BMC Pulmonary Medicine

The role of rhIGF-1/BP3 in the prevention of pulmonary hypertension in bronchopulmonary dysplasia and its underlying mechanism

日期：2023-06-15 IF：3.1
International Journal of Stem Cells

Bie Jia Jian Pill Combined with Bone Mesenchymal Stem Cells Regulates microRNA-140 to Suppress Hepatocellular Carcinoma Stem Cells

日期：2021-08-30 IF：3.011
BMC BIOINFORMATICS

Identification and validation of the shared signature gene MMP9 and ANGPTL4 and its regulatory mechanisms in Type 2 Diabetes combined with Osteoarthritis

日期：2024-06-07 IF：3
bioRxiv

5β-Dihydrotestosterone reveals a mutant androgen receptor vulnerability in prostate cancer

日期：2026-07-15 IF：3
Molecular Medicine Reports

Cinnamaldehyde inhibits psoriasis?like inflammation by suppressing proliferation and inflammatory response of keratinocytes via inhibition of NF?κB and JNK signaling pathways

日期：2021-07-07 IF：2.952
Discover Oncology

Uncovering GSTK1 and PTGER3 as biomarkers for breast cancer prognosis through comprehensive analyses

日期：2025-12-23 IF：2.9
Discover Oncology

Unraveling the interrelationship between breast cancer and endometriosis based on multi-omics analysis

日期：2025-06-13 IF：2.9
Infection and Drug Resistance

Validation of Senescence of the Role of ATM/P53 Pathway in Myocardial Senescence in Mice with Sepsis

日期：2025-04-18 IF：2.9
Journal of Molecular Histology

Blue light-emitting diode promotes mineralization of stem cells from the apical papilla via cryptochrome 1/Wnt/β-catenin signaling

日期：2025-04-01 IF：2.9
PLoS One

Key extracellular proteins and TF-miRNA co-regulatory network in diabetic foot ulcer: Bioinformatics and experimental insights

日期：2024-07-22 IF：2.9
Clinics

Exosomal miR-152-5p and miR-3681-5p function as potential biomarkers for ST-segment elevation myocardial infarction

日期：2022-06-22 IF：2.898
Computational and Mathematical Methods in Medicine

Long Noncoding RNA Zinc Finger Antisense 1 Affects Glucocorticoid-Induced Osteonecrosis of the Femoral Head by Performing as a ceRNA for MicroRNA-124-3p and Accelerating Transforming Growth Factor Type III Receptor

日期：2022-07-18 IF：2.809
Molecular Biology Reports

The expression patterns of Interleukin-26, Interleukin-35, and signal transducer and activator of transcription 1 in Type1 diabetes patients with diabetic nephropathy

日期：2026-03-13 IF：2.8
Molecular Biology Reports

Thymoquinone regulates RSL3-induced ferroptosis in the alzheimer mouse hippocampus

日期：2025-09-11 IF：2.8
MOLECULAR BIOLOGY REPORTS

Role of N6-methyladenosine methylation in transverse aortic constriction-induced cardiac fibrosis: insights from MeRIP-seq analysis

日期：2025-08-11 IF：2.8
EUROPEAN JOURNAL OF MEDICAL RESEARCH

Tumor-derived exosomal miR-21-5p mediates lung fibroblasts activation via TNFAIP3/NF-kB signaling to promote non-small cell lung cancer cell migration and invasion

日期：2024-12-19 IF：2.8
Cell Division

ZEB2 reduction contributes to pre-eclampsia via Wnt/β-Catenin pathway

日期：2024-11-29 IF：2.8
JOURNAL OF PHARMACY AND PHARMACOLOGY

Mesenchymal stem cell-derived exosomal microRNA-367-3p mitigates lower limb ischemia/reperfusion injury in mouse skeletal muscle via EZH2 targeting

日期：2024-08-13 IF：2.8
Discover Oncology

Novel curcumin derivative DMC-GF suppresses glioblastoma growth by targeting MAPK1 and TRIM21 to modulates STAT3/AKT phosphorylation

日期：2026-07-31 IF：2.78
Immunity, Inflammation and Disease

Albiflorin Relieves Intervertebral Disc Degeneration Through Inhibiting Nucleus Pulposus Cell via the p38 MAPK/NF-κB Pathway

日期：2026-03-07 IF：2.7
Immunity, Inflammation and Disease

RANKL Attenuates Sepsis-Associated Acute Lung Injury Through the OPG/RANKL/RANK/TLR4 Pathway

日期：2026-03-06 IF：2.7
Immunity Inflammation and Disease

PRKACB Attenuates Chondrocyte Loss and Inflammation in Osteoarthritis

日期：2026-02-12 IF：2.7
Immunity, Inflammation and Disease

PLSCR1 Regulates the Physiology of Fibroblast-Like Synoviocytes via Modulating the STAT1 Signaling Pathway

日期：2025-10-17 IF：2.7
BMC Pharmacology and Toxicology

Kaempferol regulates Ewing sarcoma progression via miR-26b-5p-mediated expression of the family with sequence similarity 98 member A

日期：2025-09-22 IF：2.7
Immunity Inflammation and Disease

PRKACB Attenuates Chondrocyte Loss andInflammation in Osteoarthritis

日期：2026-05-21 IF：2.7
Immunity Inflammation and Disease

PRKACB Attenuates Chondrocyte Loss andInflammation in Osteoarthritis

日期：2026-05-21 IF：2.7
Innate Immunity

MMP9 protects against LPS-induced inflammation in osteoblasts

日期：2019-11-19 IF：2.68
Pharmacogenomics & Personalized Medicine

GABRP is a Promising Prognostic Biomarker and Associated with Immune Cell Infiltration in Lung Squamous Cell Carcinoma

日期：2023-04-15 IF：2.606
PLoS One

NSUN4-mediated m5C RNA methylation protects retinal cells against excitotoxic injury via the SHH signaling pathway

日期：2026-03-15 IF：2.6
Photodiagnosis and Photodynamic Therapy

Evaluating the Impact of Febuxostat on 5-Aminolevulinic Acid-Based Photodynamic Therapy in Bladder Cancer Cell Lines

日期：2025-11-19 IF：2.6
PLOS One

LncRNA RP11-818O24.3 regulates proliferation and differentiation of hair follicle stem cells by targeting FGF2/PI3K/AKT pathway

日期：2025-07-14 IF：2.6
Molecular Biology Reports

Poricoic acid a ameliorates high glucose-induced podocyte injury by regulating the AMPKα/FUNDC1 pathway

日期：2024-09-21 IF：2.6
BMC Oral Health

Effects of Porphyromonas gingivalis lipopolysaccharide on the behavior of human dental pulp stem cells in vitro and their inflammation-related transcriptomics profile

日期：2024-08-20 IF：2.6
DNA and Cell Biology

Bone Marrow Mesenchymal Stem Cells–Derived Extracellular Vesicle miR-208a-3p Alleviating Spinal Cord Injury via Regulating the Biological Function of Spinal Cord Neurons

日期：2024-08-12 IF：2.6
Brain and Behavior

The antidepressant effect of Shexiang Baoxin Pills on myocardial infarction rats with depression may be achieved through the inhibition of the NLRP3 inflammasome pathway

日期：2024-07-05 IF：2.6
Journal of Orthopaedic Surgery and Research

Inhibition of cc chemokine receptor 10 ameliorates osteoarthritis via inhibition of the phosphoinositide-3-kinase/Akt/mammalian target of rapamycin pathway

日期：2024-03-01 IF：2.6
Journal of Orthopaedic Surgery and Research

Aberrant expression of miR-33a-3p/IGF2 in postmenopausal osteoporosis patients and its role and mechanism in osteoporosis

日期：2023-07-06 IF：2.6
BMC Gastroenterology

ITPR1 mediates the PI3K/AKT/mTOR pathway to regulate cellular autophagy, affecting lipopolysaccharide-induced pediatric inflammatory bowel disease

日期：2026-03-16 IF：2.6
International Journal of Medical Sciences

Left Stellate Ganglion Ablation Inhibits Ventricular Arrhythmias through Macrophage Regulation in Canines with Acute Ischemic Stroke

日期：2021-01-01 IF：2.557
Pharmacology

Daphnetin Preconditioning Decreases Cardiac Injury and Susceptibility to Ventricular Arrhythmia following Ischaemia-Reperfusion through the TLR4/MyD88/NF-Κb Signalling Pathway

日期：2021-04-26 IF：2.547
AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Calycosin Protects Against Chronic Prostatitis via Regulating Cellular Pyroptosis

日期：2025-05-11 IF：2.5
World Journal of Gastrointestinal Oncology

Effects of Helicobacter pylori and Moluodan on the Wnt/β-catenin signaling pathway in mice with precancerous gastric cancer lesions

日期：2024-03-15 IF：2.5
Current Molecular Medicine

Study on the Mechanism of Estrogen Regulating Endometrial Fibrosis After Mechanical Injury Via MIR-21-5P/PPARΑ/FAO Axis

日期：2023-02-28 IF：2.5
TISSUE & CELL

Ablation of ASF1B mitigates the proliferation of A549 cells and enhances anti-PD-L1 therapy by regulating ferroptosis

日期：2026-05-02 IF：2.5
BMC Nephrology

INHBA knockdown inhibits renal fibrosis in mice following ischemia–reperfusion injury by suppressing activation of the TGF-β/Smad signaling pathway

日期：2025-09-01 IF：2.4
Biochemical Genetics

Effects of KLF11 on Vascular Smooth Muscle Cells and its Underlying Mechanisms in Intracranial Aneurysm

日期：2024-02-18 IF：2.4
Journal of Natural Medicines

Bie Jia Jian pill enhances the amelioration of bone mesenchymal stem cells on hepatocellular carcinoma progression

日期：2021-07-23 IF：2.343
Biomed Research International

Yinchenhao Decoction Protects Against Intrahepatic Cholestasis During Pregnancy Through the miR-370-3p/TM9SF4/KIT Axis

日期：2025-07-26 IF：2.3
Cytotechnology

PABPC1 silencing inhibits pancreatic cancer cell proliferation and EMT, and induces apoptosis via PI3K/AKT pathway

日期：2024-04-22 IF：2.2
CYTOTECHNOLOGY

Homoharringtonine in combination with Tanshinone IIA suppresses the progression of lymphoma cells by downregulating the Akt/MMP signaling pathway

日期：2026-07-10 IF：2.2
BMC Cardiovascular Disorders

Adenosine 2 receptor regulates autophagy and apoptosis to alleviate ischemia reperfusion injury in type 2 diabetes via IRE-1 signaling

日期：2023-03-24 IF：2.174
EUROPEAN JOURNAL OF HISTOCHEMISTRY

Cryptotanshinone alleviates DSS-induced colitis in mouse by regulating the balance of Treg/Th17 cells and M1 macrophage activation

日期：2026-02-24 IF：2.1
Journal of Investigative Surgery

Role of SFRP5 in Non-Small Cell Lung Cancer and Its Correlation with SUV of 18F-FDG PET-CT

日期：2024-07-29 IF：2.1
Biochemical Genetics

Exosomal miR-17-92 Cluster from BMSCs Alleviates Apoptosis and Inflammation in Spinal Cord Injury

日期：2024-07-03 IF：2.1
Open Medicine

ANO6 (TMEM16F) inhibits gastrointestinal stromal tumor growth and induces ferroptosis

日期：2024-05-15 IF：2.1
Open Medicine

circRNA THBS1 silencing inhibits the malignant biological behavior of cervical cancer cells via the regulation of miR-543/HMGB2 axis

日期：2023-05-07 IF：2.1
Reproductive Biology

circPLOD2 knockdown suppresses endometriosis progression via the miR-216a-5p/ZEB1 axis

日期：2023-03-12 IF：2.09
Andrologia

Association of Wet Cupping With Sperm Quality and Mitochondrial Gene Expression in a Rat Model of Metabolic Male Infertility

日期：2025-08-04 IF：2
BMC Cardiovascular Disorders

Polyethylene glycol loxenatide protects diabetic kidneys by inhibiting GRP78/PERK/ eIF2α pathway, and improves cardiac injury by suppressing TLR4/NF-κB infammatory pathway

日期：2024-12-18 IF：2
Oncology Research

Remodeling tumor microenvironment using pH-sensitive biomimetic co-delivery of TRAIL/R848 liposomes against colorectal cancer

日期：2024-10-16 IF：2
Skin Research and Technology

Proanthocyanidins alleviate Henoch-Sch?nlein purpura by mitigating inflammation and oxidative stress through regulation of the TLR4/MyD88/NF-κB pathway

日期：2024-09-10 IF：2
European Journal of Histochemistry

Tumor cells-derived exosomal PD-L1 promotes the growth and invasion of lung cancer cells in vitro via mediating macrophages M2 polarization

日期：2023-08-01 IF：2
European Journal of Histochemistry

Combination of tolvaptan and valsartan improves cardiac and renal functions in doxorubicin-induced heart failure in mice

日期：2022-11-11 IF：1.966
European Journal of Histochemistry

Long non-coding RNA WAC antisense RNA 1 mediates hepatitis B virus replication in vitro by reinforcing miR-192-5p/ATG7-induced autophagy

日期：2022-09-02 IF：1.966
European Journal of Histochemistry

Polydatin reverses oxidation low lipoprotein (oxLDL)-induced apoptosis of human umbilical vein endothelial cells via regulating the miR-26a-5p/BID axis

日期：2022-09-02 IF：1.966
European Journal of Histochemistry

Docetaxel-resistant triple-negative breast cancer cell-derived exosomal lncRNALINC00667 reduces the chemosensitivity of breast cancer cells to docetaxel viatargeting miR-200b-3p/Bcl-2 axis

日期：2022-10-25 IF：1.966
European Journal of Histochemistry

VEGF promotes diabetic retinopathy by upregulating the PKC/ET/NF-κB/ICAM-1 signaling pathway

日期：2022-10-27 IF：1.966
INDIAN JOURNAL OF OPHTHALMOLOGY

Notch 3 regulates ferroptosis of lens epithelial cells in age-related cataract by PI3K/AKT pathway

日期：2026-02-02 IF：1.9
INTERNATIONAL JOURNAL OF ENVIRONMENTAL HEALTH RESEARCH

Roles on antiproliferation, apoptosis, necrosis and proinflammation of Micromeria fruticosa subsp. brachycalyx essential oil obtained by hydrodistillation on lung cancer cells

日期：2025-07-09 IF：1.9
JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

RAB5A Governs Synovial Fibroblast Extracellular Vesicles and Mediates Chondrocyte Degeneration in Osteoarthritis

日期：2026-03-07 IF：1.8
CELL BIOCHEMISTRY AND BIOPHYSICS

TREM2 Impairs Glycolysis to Interrupt Microglial M1 Polarization and Inflammation via JAK2/STAT3 Axis

日期：2024-09-06 IF：1.8
Open Medicine

Aloe emodin attenuates Aβ1–42-Induced neurotoxicity in SH-SY5Y cells via downregulation of PPM1K

日期：2026-07-07 IF：1.8
Experimental and Therapeutic Medicine

Analysis of piRNA expression spectra in a non?alcoholic fatty liver disease mouse model induced by a methionine?and choline?deficient diet

日期：2020-04-09 IF：1.73
Cytotechnology

IGFBP7 inhibition relieves LPS induced nucleus pulposus cell injury by regulating the ERK1/2 pathway

日期：2025-06-06 IF：1.7
Open Medicine

Signi?cant role and the underly mechanism of cullin-1 in chronic obstructive pulmonary disease

日期：2024-11-18 IF：1.7
Open Medicine

Dioscin protects against chronic prostatitis through the TLR4/NF-κB pathway

日期：2024-08-20 IF：1.7
Open Medicine

METTL3 blocked the progression of diabetic retinopathy through m6A-modi?ed SOX2

日期：2025-03-21 IF：1.6
Biochemical Genetics

Neuroprotective Role of THBS2 in Experimental Spinal Cord Injury Via its Anti-neuroinflammatory and Anti-apoptotic Properties

日期：2025-06-26 IF：1.6
Genes & Genomics

Roles and action mechanisms of NRIP1 in pre-eclampsia

日期：2024-09-13 IF：1.6
Revista Brasileira de Farmacognosia

Effects of Liquiritin on Mitochondrial Dynamics in Cerebral Ischemia–Reperfusion Injury by Regulating Nurr1 via the YAP-INF2-Mitochondrial Fission Pathway

日期：2023-12-28 IF：1.6
Revista Brasileira de Farmacognosia-Brazilian Journal of Pharmacognosy

Panax notoginseng Saponins Play a Protective Role in Acute Cerebral Infarction by Regulating lncRNA SNHG15

日期：2023-11-11 IF：1.6
BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH

MMP9 regulates osteogenesis and MMP2 expression through the TGF-β1/SMAD2/3 signaling pathway in lipopolysaccharide-induced osteoblasts

日期：2026-01-20 IF：1.5
THERAPEUTIC APHERESIS AND DIALYSIS

Influence of Huaiqihuang granule on peritoneal fibrosis induced by peritoneal dialysis: A study based on rat model

日期：2025-05-14 IF：1.5
Journal of Cardiothoracic Surgery

SNX30 inhibits lung adenocarcinoma cell proliferation and induces cell ferroptosis through regulating SETDB1

日期：2025-01-09 IF：1.5
Journal of Cardiothoracic Surgery

Atractylenolide II alleviates LPS-induced acute lung injury in A549 cells via the TNIP2/NF-κB pathway

日期：2026-04-16 IF：1.5
Revista Brasileira de Farmacognosia

Icariside II Suppresses the Malignant Behaviors of Breast Cancer Cells by Inhibiting PTGES3 Expression

日期：2024-08-30 IF：1.4
Revista Brasileira de Farmacognosia-Brazilian Journal of Pharmacognosy

Shionone Exhibits Anti-inflammatory and Antiproliferative Effects in Pulmonary Arterial Endothelial Cells and Smooth Muscle Cells via SIRT1 in Pulmonary Arterial Hypertension

日期：2024-07-29 IF：1.4
International Heart Journal

Exosomal MiR-223-3p from Adipose-Derived Stem Cells Alleviates Hypoxia/Reoxygenation-Induced Ferroptosis of H9c2 Cells by Inhibiting TFRC

日期：2026-02-05 IF：1.3
PHARMAZIE

Effects of different concentrations of metformin on osteoclast differentiation and apoptosis and its mechanism

日期：2021-08-21 IF：1.267
Genetic Testing and Molecular Biomarkers

Functional Characterization of Plasminogen Activator Urokinase as a Key Gene in Papillary Thyroid Carcinoma Lymph Node Metastasis

日期：2025-06-02 IF：1.1
Indian Journal of Experimental Biology

Antiproliferative, anti-inflammatory, antitumoral and proapoptotic effects of calcitriol on MCF-7 and MCF-10A cell lines

日期：2023-05-01 IF：0.944
Journal of Biobased Materials and Bioenergy

Liquid Chromatography-Mass Spectrometry Characterized Hydrolysate Fractions Possess Anticancer Activity In Vitro

日期：2022-02-01 IF：0.708
BOLETIN LATINOAMERICANO Y DEL CARIBE DE PLANTAS MEDICINALES Y AROM?TICAS

Possible induction of apoptotic and necrotic death pathways in lung cancer cells by Clinopodium vulgareL. and phenolic acids and flavonoids detection by LC-MS-MS

日期：2024-05-26 IF：0.7

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