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CD4 Mouse mAb
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EM1070
意大利贵宾会-贵宾会官方网站入口规格: 意大利贵宾会-贵宾会官方网站入口价钱:
50?L ¥1280.00
100?L ¥1980.00

Overview

产品名称: CD4 Mouse mAb
反应性: Human, Rat, Mouse
又名: CD4 molecule, CD4mut
宿主: Mouse
稀释比: IHC 1:100-200
免疫原: Synthetic Peptide
贮存条件: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid?repeated?freeze-thaw?cycles.
克隆性: Monoclonal
抗体亚型: IgG1
浓度: 1mg/mL
基因ID: 920
卵白序列: P01730
细胞定位: Cell membrane
研究配景: In molecular biology, CD4 (cluster of differentiation 4) is a glycoprotein found on the surface of immune cells such as T helper cells, monocytes, macrophages, and dendritic cells. It was discovered in the late 1970s and was originally known as leu-3 and T4 (after the OKT4 monoclonal antibody that reacted with it) before being named CD4 in 1984. In humans, the CD4 protein is encoded by the CD4 geneGalectin 3 is one of the more extensively studied members of this family and is a 30 kDa protein. Due to a C-terminal carbohydrate binding site, Galectin 3 is capable of binding IgE and mammalian cell surfaces only when homodimerized or homooligomerized. Galectin 3 is normally distributed in epithelia of many organs, in various inflammatory cells, including macrophages, as well as dendritic cells and Kupffer cells. The expression of this lectin is up-regulated during inflammation, cell proliferation, cell differentiation and through trans-activation by viral proteins.
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