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MAP2 Mouse mAb
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EM1067
意大利贵宾会-贵宾会官方网站入口规格： 意大利贵宾会-贵宾会官方网站入口价钱：
50?L ￥1280.00
100?L ￥1980.00

Overview 文献(1)

产品名称: MAP2 Mouse mAb
反应性: Human, Rat, Mouse
又名: MAP2A, MAP2B, MAP2C
宿主: Mouse
稀释比: IHC 1:200
免疫原: Synthetic Peptide
贮存条件: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid?repeated?freeze-thaw?cycles.
克隆性: Monoclonal
抗体亚型: IgG1
浓度: 1mg/mL
基因ID: 4133
卵白序列: P11137
细胞定位: Cytoplasm, cytoskeleton.
研究配景: MAP2 is the major microtubule associated protein of brain tissue. There are three forms of MAP2; two are similarily sized with apparent molecular weights of 280 kDa (MAP2a and MAP2b) and the third with a lower molecular weight of 70 kDa (MAP2c). In the newborn rat brain, MAP2b and MAP2c are present, while MAP2a is absent. Between postnatal days 10 and 20, MAP2a appears. At the same time, the level of MAP2c drops by 10-fold. This change happens during the period when dendrite growth is completed and when neurons have reached their mature morphology. MAP2 is degraded by a Cathepsin D-like protease in the brain of aged rats. There is some indication that MAP2 is expressed at higher levels in some types of neurons than in other types. MAP2 is known to promote microtubule assembly and to form side-arms on microtubules. It also interacts with neurofilaments, actin, and other elements of the cytoskeleton.
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    意大利贵宾会-贵宾会官方网站入口日期：2023-02-05 意大利贵宾会-贵宾会官方网站入口IF：5.1
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