MAPK, Mitogen-activated protein Kinase, PRKM2,MK01
宿主:
Rabbit
稀释比:
WB 1:1,000-2,000 IHC 1:50-100
免疫原:
Recombinant Protein
贮存条件:
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid?repeated?freeze-thaw?cycles.
克隆性:
Polyclonal
抗体亚型:
IgG
浓度:
1mg/mL
实测条带:
44,42kDa
基因ID:
5594/5595
卵白序列:
P27361/P28482
细胞定位:
Nucleus
研究配景:
Mitogen-activated protein kinases (MAPKs) are a widely conserved family of serine/threonine protein kinases involved in many cellular programs such as cell proliferation, differentiation, motility, and death. The p44/42 MAPK (Erk1/2) signaling pathway can be activated in response to a diverse range of extracellular stimuli including mitogens, growth factors, and cytokines and is an important target in the diagnosis and treatment of cancer.
lift
Antitumor Effects of Quercetin and Luteolin in A375 Cutaneous Melanoma Cell Line Are Mediated by Upregulation of P-ERK, c-Myc, and the Upstream GPER