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COX2/Cyclooxygenase 2 Rabbit pAb
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EA024
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50?L ¥1280.00
100?L ¥1980.00

Overview

产品名称: COX2/Cyclooxygenase 2 Rabbit pAb
反应性: Human
又名: Cyclooxygenase 2, GRIPGHS, hCox 2, PGG/HS, PGH synthase 2, PGHS 2, PHS 2, PHS II, Prostaglandin G/H synthase 2, Prostaglandin H2 synthase 2, PTGS2
宿主: Rabbit
稀释比: WB 1:1,000 IHC 1:100
免疫原: Synthetic Peptide
贮存条件: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid?repeated?freeze-thaw?cycles.
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1mg/mL
实测条带: 70kDa
基因ID: 5743
卵白序列: P35354
研究配景: Prostaglandin-endoperoxide synthase 2, also known as cyclooxygenase-2 or simply COX-2, is an enzyme that in humans is encoded by the PTGS2 gene. There are two isozymes of COX encoded by distinct gene products: a constitutive COX-1 (this enzyme) and an inducible COX-2, which differ in their regulation of expression and tissue distribution. The expression of these two transcripts is differentially regulated by relevant cytokines and growth factors. A splice variant of COX-1 termed COX-3 was identified in the CNS of dogs, but does not result in a functional protein in humans. Two smaller COX-1-derived proteins (the partial COX-1 proteins PCOX-1A and PCOX-1B) have also been discovered, but their precise roles are yet to be described.
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